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ACE-031 is a fusion protein that has been explored as a potential treatment for several health issues related to muscle loss and bone strength. Clinical studies indicate that it may promote muscle growth, enhance bone density, and help decrease fat mass. This makes it a promising option for addressing conditions such as Duchenne muscular dystrophy (DMD), sarcopenia, and osteosarcopenia.
Several trials have been conducted to assess its safety and how the body metabolizes the peptide, along with its overall impact. Findings so far have shown gains in lean body mass and enhancements in physical performance. for those involved in the studies. Although its development faced a setback due to concerns about safety, it continues to be a significant area of research aimed at improving muscle and bone health, especially in patients with chronic conditions.
Buy ACE-031 Peptide 1mg Vial from Peptide Works. This lyophilized powder is over 98% pure. It is available as a kit, including bacteriostatic water for reconstitution and syringes.
ACE-031 is a myostatin inhibitor, designed to help boost muscle growth. Myostatin is a protein in the body that naturally limits how much muscle you can build. It works by attaching to a receptor on muscle cells called activin receptor type IIB (ActRIIB), sending signals to slow down muscle development.
ACE-031, from Peptide Works, acts like a “decoy” receptor. The peptide mimics ActRIIB and binds to myostatin first, blocking it from reaching its real receptor. This helps muscles to grow and repair more effectively. It can also interact with other proteins, like activins, which influence muscle hypertrophy. While promising for muscle-wasting conditions, further research is needed to address safety concerns in clinical trials.
Promotes Muscle Growth and Strength: Research shows it blocks myostatin through a soluble form of activin receptor type IIB, which helps promote muscle growth and increase strength [1]. Studies have found significant gains in muscle force without affecting energy levels, making it a potential option for treating conditions like muscular dystrophy [2].
Potential Treatment For Muscle Wasting Disorders: The peptide shows potential in treating muscle-wasting conditions like sarcopenia, muscular dystrophies, and cancer-related cachexia. Myostatin, a protein that regulates muscle loss and growth, is essential for maintaining healthy skeletal muscles.
By blocking myostatin, ACE-031 supports muscle growth and improves muscle function. This aligns with 2023 research highlighting the regenerative potential of skeletal muscle and its vital role in maintaining stability, mobility, and overall musculoskeletal health, offering hope for therapeutic advancements [3].
Improved Bone Health:Research shows that the 031 ACE peptide can improve bone health by boosting bone density and mass through its impact on osteoblast and osteoclast activity. It also shows potential in treating osteosarcopenia, a condition that combines osteoporosis and muscle loss. While safety concerns have paused clinical development, the peptide underscores the importance of targeting myostatin to improve both bone and muscle health in dual management strategies [4].
Potential Treatment for Chronic Diseases: Studies suggest it shows promise for chronic diseases, such as Duchenne muscular dystrophy (DMD). Clinical trials on ambulatory boys with Duchenne muscular dystrophy revealed potential benefits like improved lean body mass, lower fat mass, and better bone mineral density. While there were a few safety concerns, the study highlighted the significant potential of myostatin inhibition as an effective approach for preserving muscle function and improving quality of life in the management of chronic diseases [5].
Buy ACE-031 Pre-Mixed Peptide from Peptide Works. Each pen kit includes 1mg pre-mixed cartridges, supplied with a cartridge pen, needle tips, and carry case for accuracy and ease of use.
[1] Kenneth M Attie, Niels G Borgstein, Yijun Yang, Carolyn H Condon, et al (2013) A single ascending-dose study of muscle regulator ACE-031 in healthy volunteers – Muscle Nerve, 2013 Mar, Volume 47 (Issue 3), Pages 416-23.
[2] Hiroyasu Muramatsu, Taichi Kuramochi, Hitoshi Katada, Atsunori Ueyama, et al (2021) Novel myostatin-specific antibody enhances muscle strength in muscle disease models – Scientific Reports , 25 January 2021, Volume 11, Article number: 2160.
The answers to the most frequently asked questions about ACE-031.
Buy ACE-031 Peptide Nasal Spray from Peptide Works. The spray is available in 15ml and 30ml glass spray bottles.
Myostatin is a protein that helps control muscle growth. It belongs to the transforming growth factor-beta (TGF-β) family and is mainly produced in skeletal muscle cells. It limits muscle growth by preventing muscle cells from dividing and growing. High myostatin levels reduce muscle mass, while lower levels increase it. This makes myostatin a key focus in research on muscle-wasting diseases, athletic performance, and livestock breeding.
It has potential in treating muscle-wasting diseases like muscular dystrophy, sarcopenia, and cachexia.
Whilst it has shown promise, clinical trials have raised a few safety concerns. There have been reports of side effects like nosebleeds and increased blood pressure. Further research is needed.
These products are not approved for human use or consumption and are only available for research purposes under controlled conditions. They have not been approved by regulatory bodies such as the United States Food and Drug Administration (FDA).
ACE-031 is a synthetic protein that targets muscle growth by blocking myostatin, acting like its receptor. Follistatin 344, in contrast, is a natural glycoprotein that blocks myostatin along with other growth factors. Both peptides show potential for treating muscle-wasting diseases, but work in different ways and may have different side effects.
Explore the science behind muscle growth with ACE-031 and Follistatin 344. Learn how these myostatin inhibitors work, compare their muscle-building results, and review key study findings. Get insights to drive your muscle growth research forward.
Discover how peptide ACE-031, a myostatin inhibitor, shows promise in fat reduction research in this blog. Learn how it enhances lean muscle mass, boosts fat metabolism, and improves metabolic flexibility.
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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Peptide Works website: https://peptide-works.com/ is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
