PROMO!
First order? Get 10% OFF with this code: 1storder
Our Blog
Discover the latest blog posts from Peptide Works
Discover how researchers measure AMPK activity using methods including Thr172 phosphorylation analysis, downstream substrate phosphorylation and direct kinase activity assays to characterise AMPK-associated signalling.
B7-33 provides a useful case study in peptide structure-activity research. This article examines how lipidation has been investigated as a structural modification and why in vitro stability and measured activity need to be treated as separate experimental endpoints.
Much of the laboratory research on LL-37 has focused on how the peptide behaves around microbial membranes, bacterial components, and biofilms.
Pinealon has undergone investigation in cell-based studies which involved controlled experimental challenges. This review examines the measurements that were taken, such as those of reactive oxygen species, ERK1/2 signaling, and cell viability, while separating the observations that have been reported from the mechanisms which are still unconfirmed.
AMP-activated protein kinase, commonly referred to as AMPK, is a protein kinase that plays a role in how cells respond to changes in energy availability. Research concerning AMPK is directed towards understanding how cells detect changes in their energy status and then adjust the various intracellular pathways related to glucose handling, lipid metabolism, mitochondrial function, and autophagy.
This blog examines how myostatin (GDF-8) signalling is studied in skeletal muscle research, focusing on receptor interactions, SMAD signalling, pathway regulation, and the experimental methods used to measure its activity.
Article & News
This blog compares Semax and Selank by examining their structural differences, molecular pathways and experimentally measured endpoints in peptide research.
Oxytocin is a nine-amino-acid peptide involved in a signaling system extending from hypothalamic synthesis to oxytocin receptor activation. Experimental research examines this system at molecular, cellular, and neural-circuit levels, making its biology considerably more complex than the familiar description of oxytocin as the “love hormone”.
Myostatin, also known as GDF-8, is regulated through a series of molecular steps involving precursor processing, latency and extracellular activation. This article examines how researchers investigate these processes and the different experimental approaches used to study myostatin inhibition.
Research carried out in the laboratory has looked into Epithalon as regards signaling associated with the pineal gland, the pathways involved in the synthesis of melatonin, and intracellular regulation. The present article focuses on the cellular and molecular endpoints that were studied in these experimental models.
